产品货号：
Z20331
中文名称：
MIS12抗体
英文名称：
Anti-MIS12 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MIS12 Antibody |
| 指标别名 | 2510025F08Rik;hMis12;KNTC2AP;MIS12;MTW1;Protein MIS12 homolog |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,ICC/IF,FCM(Intracellular),ELISA |
| 基因名称 | MIS12 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human MIS12 recombinant protein (Position:M1-K187). |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Protein MIS12 homolog is a protein that in humans is encoded by the MIS12 gene.Mis12 complex is composed of four subunits,Protein MIS12 homolog,Polyamine-modulated factor 1,Kinetochore-associated protein DSN1 homolog,and Kinetochore-associated protein NSL1 homolog (UniProt:Q9H081,Q6P1K2,Q9H410,Q96IY1,respectively) that are encoded by genes known as MIS12 (Gene ID:79003),PMF1 (Gene ID:100527963),DSN1 (Gene ID:79980),and NSL1 (also known as C1orf48,DC31,DC8,MIS14) (Gene ID:25936) in human.The MIS12 complex is a protein interaction hub for outer kinetochore assembly.This complex acts as the primary microtubule-binding interface at kinetochores and provides a platform to recruit regulatory proteins.In human Mis12 complex subunits are shown to localize with centromere protein A (CENP-A) at inner kinetochores and internally to Ndc80 at outer kinetochores.Mis12 complex plays an essential role in chromosome segregation in vertebrates and contributes to mitotic kinetochore assembly.Reduced levels of Mis12 complex proteins are shown to result in chromosome alignment defects in both human and chicken cells,but spindle bipolarity is not disturbed. |
| Uniprot ID | Q9H081 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for ICC. |
| 基因名全称 | MIS12 kinetochore complex component |
| 蛋白名全称 | Protein MIS12 homolog |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow Cytometry(Intracellular) 1～3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100～1000 |
| Gene ID | 54069 |
相关搜索：MIS12抗体，MIS12多抗，Anti-MIS12 Antibody